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    swi10 DNA repair endonuclease non-catalytic (ERCC1) subunit Swi10 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540887, updated on 18-Sep-2024

    Summary

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    Official Symbol
    swi10
    Official Full Name
    DNA repair endonuclease non-catalytic (ERCC1) subunit Swi10
    Primary source
    PomBase:SPBC4F6.15c
    Locus tag
    SPOM_SPBC4F6.15C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rad23
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    Genomic context

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    See swi10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (2718967..2720232, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene WD repeat/BOP1NT protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ER oxidoreductin Ero1a Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular identification and characterization of peptide: N-glycanase from Schizosaccharomyces pombe. Xin F, et al. Biochem Biophys Res Commun, 2008 Apr 18. PMID 18279662
    2. The rad16 gene of Schizosaccharomyces pombe: a homolog of the RAD1 gene of Saccharomyces cerevisiae. Carr AM, et al. Mol Cell Biol, 1994 Mar. PMID 8114734, Free PMC Article
    3. Mutagenesis of the HMGB (high-mobility group B) protein Cmb1 (cytosine-mismatch binding 1) of Schizosaccharomyces pombe: effects on recognition of DNA mismatches and damage. Kunz C, et al. Biochem J, 2003 Jun 1. PMID 12617726, Free PMC Article
    4. The genetic control of spontaneous and UV-induced mitotic intrachromosomal recombination in the fission yeast Schizosaccharomyces pombe. Osman F, et al. Curr Genet, 2000 Oct. PMID 11057444
    5. Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair. Fleck O, et al. Nat Genet, 1999 Mar. PMID 10080187

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables damaged DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to single-stranded DNA endodeoxyribonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in UV-damage excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via single-strand annealing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in gene conversion at mating-type locus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mating type switching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ERCC4-ERCC1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    part_of nucleotide-excision repair factor 1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nucleotide-excision repair factor 1 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA repair endonuclease non-catalytic (ERCC1) subunit Swi10

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2718967..2720232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022032.3 → NP_596115.1  DNA repair endonuclease non-catalytic (ERCC1) subunit Swi10 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596115.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q06182
      Conserved Domains (3) summary
      COG5241
      Location:1 → 236
      RAD10; Nucleotide excision repair endonuclease NEF1, RAD10 subunit [DNA replication, recombination, and repair]
      pfam03834
      Location:42 → 155
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      pfam14520
      Location:179 → 233
      HHH_5; Helix-hairpin-helix domain
    Nucleotide Protein
    Heading Accession and Version

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