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    mpg2 mannose-1-phosphate guanyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539751, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mpg2
    Official Full Name
    mannose-1-phosphate guanyltransferase
    Primary source
    PomBase:SPBC13G1.02
    Locus tag
    SPOM_SPBC13G1.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mpg2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3729722..3731389)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene RNA helicase Neighboring gene putative RNA-binding protein Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein uS4m Neighboring gene ncRNA Neighboring gene protein Pex14 Neighboring gene folding protein Neighboring gene alpha-ketoglutarate-dependent dioxygenase Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly protein Isd11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mpg2 interacts and cooperates with Mpg1 to maintain yeast glycosylation. Muñoz-Centeno MC, et al. FEMS Yeast Res, 2012 Aug. PMID 22416758
    2. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
    3. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mannose-1-phosphate guanylyltransferase (GTP) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in GDP-mannose biosynthetic process IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mannose-1-phosphate guanyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3729722..3731389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022472.3 → NP_596551.1  mannose-1-phosphate guanyltransferase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596551.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60064
      Conserved Domains (3) summary
      cd06428
      Location:5 → 265
      M1P_guanylylT_A_like_N; N-terminal domain of M1P_guanylyl_A_ like proteins are likely to be a isoform of GDP-mannose pyrophosphorylase
      COG1208
      Location:5 → 404
      GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]
      cl00160
      Location:289 → 357
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
    Nucleotide Protein
    Heading Accession and Version

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