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    tbp1 TATA-binding protein (TBP) [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541582, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tbp1
    Official Full Name
    TATA-binding protein (TBP)
    Primary source
    PomBase:SPAC29E6.08
    Locus tag
    SPOM_SPAC29E6.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC30.12; tbp; tdf1
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    Genomic context

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    See tbp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (4415479..4417151)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene cysteine--tRNA(Cys) ligase Crs1 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene protein nst1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID. Hoffmann A, et al. Genes Dev, 1990 Jul. PMID 2210373
    2. An immunoaffinity purified Schizosaccharomyces pombe TBP-containing complex directs correct initiation of the S.pombe rRNA gene promoter. Chen L, et al. Nucleic Acids Res, 1997 Apr 15. PMID 9092673, Free PMC Article
    3. Human papillomavirus-16 E7 protein inhibits the DNA interaction of the TATA binding transcription factor. Maldonado E, et al. J Cell Biochem, 2002. PMID 11968006
    4. The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment. Huang Y, et al. Nucleic Acids Res, 2003 Apr 15. PMID 12682361, Free PMC Article
    5. Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF. Mitsuzawa H, et al. Nucleic Acids Res, 2002 May 1. PMID 11972332, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. propose that the Cnd2-TBP interaction coordinates transcription with chromosomal architecture by linking dispersed gene loci with centromeres
      Title: Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase I general transcription initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase II core promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase III general transcription initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase III type 3 promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase I promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase III promoter ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase I transcription regulator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIIIB complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    TATA-binding protein (TBP)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4415479..4417151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019995.3 → NP_594566.1  TATA-binding protein (TBP) [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594566.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P17871
      Conserved Domains (2) summary
      PLN00062
      Location:55 → 230
      PLN00062; TATA-box-binding protein; Provisional
      cd04516
      Location:55 → 228
      TBP_eukaryotes; eukaryotic TATA box binding protein (TBP): Present in archaea and eukaryotes, TBPs are transcription factors that recognize promoters and initiate transcription. TBP has been shown to be an essential component of three different transcription initiation ...
    Nucleotide Protein
    Heading Accession and Version

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