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    srb8 mediator complex subunit Med12 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543467, updated on 3-Dec-2024

    Summary

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    Official Symbol
    srb8
    Official Full Name
    mediator complex subunit Med12
    Primary source
    PomBase:SPAC688.08
    Locus tag
    SPOM_SPAC688.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    med12
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    Genomic context

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    See srb8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (3123163..3126653)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Rng10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial pyrimidine nucleotide transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mediator can regulate mitotic entry and direct periodic transcription in fission yeast. Banyai G, et al. Mol Cell Biol, 2014 Nov. PMID 25154415, Free PMC Article
    2. A chromatin-remodeling protein is a component of fission yeast mediator. Khorosjutina O, et al. J Biol Chem, 2010 Sep 24. PMID 20622008, Free PMC Article
    3. Cyclin C influences the timing of mitosis in fission yeast. Banyai G, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515143, Free PMC Article
    4. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Samuelsen CO, et al. Proc Natl Acad Sci U S A, 2003 May 27. PMID 12738880, Free PMC Article
    5. Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways. Linder T, et al. Nucleic Acids Res, 2008 May. PMID 18310102, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3123163..3126653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001430996.1 → NP_001417945.1  LOW QUALITY PROTEIN: mediator complex subunit Med12 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6L8
      UniProtKB/TrEMBL
      A0AAN2L314
    Nucleotide Protein
    Heading Accession and Version

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