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    sec2 guanyl-nucleotide exchange factor Sec2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541930, updated on 14-Nov-2024

    Summary

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    Official Symbol
    sec2
    Official Full Name
    guanyl-nucleotide exchange factor Sec2
    Primary source
    PomBase:SPAC23C4.10
    Locus tag
    SPOM_SPAC23C4.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sec2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1044910..1046788)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene chaperonin-containing T-complex associated protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F0-ATPase subunit J Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cerebral Blood Flow Alterations as Assessed by 3D ASL in Cognitive Impairment in Patients with Subcortical Vascular Cognitive Impairment: A Marker for Disease Severity. Sun Y, et al. Front Aging Neurosci, 2016. PMID 27630562, Free PMC Article
    2. A guaninine nucleotide exchange factor is a component of the meiotic spindle pole body in Schizosaccharomyces pombe. Yang HJ, et al. Mol Biol Cell, 2010 Apr 1. PMID 20130084, Free PMC Article
    3. The exocytic Rabs Ypt3 and Ypt2 regulate the early step of biogenesis of the spore plasma membrane in fission yeast. Imada K, et al. Mol Biol Cell, 2016 Nov 1. PMID 27630265, Free PMC Article
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in intracellular protein transport IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in medial cortical node IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in meiotic spindle pole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanyl-nucleotide exchange factor Sec2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1044910..1046788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018578.3 → NP_593182.1  guanyl-nucleotide exchange factor Sec2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593182.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13930
      Conserved Domains (2) summary
      pfam06428
      Location:89 → 178
      Sec2p; GDP/GTP exchange factor Sec2p
      cl23765
      Location:1 → 143
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    Nucleotide Protein
    Heading Accession and Version

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