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    vrs2 valine--tRNA (Val) ligase Vrs2/Vas2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543603, updated on 18-Sep-2024

    Summary

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    Official Symbol
    vrs2
    Official Full Name
    valine--tRNA (Val) ligase Vrs2/Vas2
    Primary source
    PomBase:SPAC4A8.08c
    Locus tag
    SPOM_SPAC4A8.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ValRS2; vas2
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    Genomic context

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    See vrs2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003424.3 (2558454..2561812, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene esterase/lipase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene sphinganine kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Cwf21 Neighboring gene lipase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe possesses two paralogous valyl-tRNA synthetase genes of mitochondrial origin. Chiu WC, et al. Mol Biol Evol, 2010 Jun. PMID 20106903
    2. Silencing mediated by the Schizosaccharomyces pombe HIRA complex is dependent upon the Hpc2-like protein, Hip4. Anderson HE, et al. PLoS One, 2010 Oct 18. PMID 20976105, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables valine-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables valine-tRNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial valyl-tRNA aminoacylation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in valyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrial matrix IC
    Inferred by Curator
    more info
    		  
    is_active_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    valine--tRNA (Val) ligase Vrs2/Vas2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2558454..2561812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019249.3 → NP_593819.1  valine--tRNA (Val) ligase Vrs2/Vas2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593819.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14160
      Conserved Domains (4) summary
      cd07962
      Location:632 → 761
      Anticodon_Ia_Val; Anticodon-binding domain of valyl tRNA synthetases
      cd00817
      Location:58 → 632
      ValRS_core; catalytic core domain of valyl-tRNA synthetases
      COG0525
      Location:31 → 950
      ValS; Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
      pfam13603
      Location:237 → 364
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    Nucleotide Protein
    Heading Accession and Version

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