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    nup189 nucleoporin Nup98 and Nup96 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541547, updated on 10-Oct-2024

    Summary

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    Official Symbol
    nup189
    Official Full Name
    nucleoporin Nup98 and Nup96
    Primary source
    PomBase:SPAC1486.05
    Locus tag
    SPOM_SPAC1486.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    nup189C; nup189N; nup96; nup98
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    Genomic context

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    See nup189 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3196965..3202450)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RNA-binding splicing factor Neighboring gene ncRNA Neighboring gene nucleoporin Alm1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F1F0 ATP synthase assembly factor Fmc1 Neighboring gene nicotinate phosphoribosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Uncleavable Nup98-Nup96 is functional in the fission yeast Schizosaccharomyces pombe. Asakawa H, et al. FEBS Open Bio, 2015. PMID 26137436, Free PMC Article
    2. The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe. Thon G, et al. Genetics, 2005 Dec. PMID 16157682, Free PMC Article
    3. The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division. Baï SW, et al. Mol Cell Biol, 2004 Jul. PMID 15226438, Free PMC Article
    4. An evolutionarily conserved fission yeast protein, Ned1, implicated in normal nuclear morphology and chromosome stability, interacts with Dis3, Pim1/RCC1 and an essential nucleoporin. Tange Y, et al. J Cell Sci, 2002 Nov 15. PMID 12376568
    5. Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. Bilokapic S, et al. Proc Natl Acad Sci U S A, 2012 Sep 18. PMID 22955883, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal subunit export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in telomere tethering at nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pore cytoplasmic filaments IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nuclear pore outer ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nucleoporin Nup98 and Nup96

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3196965..3202450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001430997.1 → NP_001417946.1  LOW QUALITY PROTEIN: nucleoporin Nup98 and Nup96 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A0E3VYD1, A0A0E4FZX7, P78796, Q9UTK4
      UniProtKB/TrEMBL
      A0AAN2L382
    Nucleotide Protein
    Heading Accession and Version

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