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    mtf1 RNA polymerase-specificity factor Mtf1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543271, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mtf1
    Official Full Name
    RNA polymerase-specificity factor Mtf1
    Primary source
    PomBase:SPAC1002.08c
    Locus tag
    SPOM_SPAC1002.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mtf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1809480..1811330, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene N-acetyltransferase Ats1 Neighboring gene ncRNA Neighboring gene bouquet formation protein Bqt2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dihydrolipoamide dehydrogenase Dld1 Neighboring gene ncRNA Neighboring gene snRNP binding protein Sgt1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe. Jiang H, et al. Nucleic Acids Res, 2011 Jul. PMID 21357609, Free PMC Article
    2. A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1. Sun W, et al. Nucleic Acids Res, 2011 Apr. PMID 21138961, Free PMC Article
    3. Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1. Sun W, et al. Genes Cells, 2012 Feb. PMID 23035257
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Deletion mutants show Mtf1 to be essential for cell growth, cell morphology and mitochondrial membrane potential.
      Title: Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe.
    2. Over expression of Mtf1 induced transcription of the srk1 gene and Mtf1 deletion led to a reduction in transcription of the srk1 gene in vivo.
      Title: A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mitochondrial transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA (adenine) methyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial transcription EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at mitochondrial promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at mitochondrial promoter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial DNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial DNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA polymerase-specificity factor Mtf1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1809480..1811330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018929.3 → NP_593495.1  RNA polymerase-specificity factor Mtf1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593495.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9US51
      Conserved Domains (1) summary
      pfam00398
      Location:26 → 350
      RrnaAD; Ribosomal RNA adenine dimethylase
    Nucleotide Protein
    Heading Accession and Version

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