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    CPP1 cysteine-rich palmitoylated domain-containing protein CPP1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852304, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CPP1
    Official Full Name
    cysteine-rich palmitoylated domain-containing protein CPP1
    Primary source
    SGD:S000000220
    Locus tag
    YBR016W
    See related
    AllianceGenome:SGD:S000000220; FungiDB:YBR016W; VEuPathDB:YBR016W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cellular bud membrane and mating projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CPP1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (270247..270633)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene glutathione-disulfide reductase GRX7 Neighboring gene alpha-1,2-mannosyltransferase MNN2 Neighboring gene Kap104p Neighboring gene UDP-glucose:hexose-1-phosphate uridylyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling. Valdez-Taubas J, et al. Curr Biol, 2003 Sep 16. PMID 13678596
    2. Palmitoylation of CYSTM (CYSPD) proteins in yeast. Giolito ML, et al. J Biol Chem, 2024 Feb. PMID 38159851, Free PMC Article
    3. Disruption and functional analysis of seven ORFs on chromosome IV: YDL057w, YDL012c, YDL010w, YDL009c, YDL008w (APC11), YDL005c (MED2) and YDL003w (MCD1). Smith KN, et al. Yeast, 1999 Sep 15. PMID 10487928
    4. CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. Venancio TM, et al. Bioinformatics, 2010 Jan 15. PMID 19933165, Free PMC Article
    5. CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Ren J, et al. Protein Eng Des Sel, 2008 Nov. PMID 18753194, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cellular bud membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mating projection membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cysteine-rich palmitoylated domain-containing protein CPP1
    NP_009572.1
    • Tail-anchored plasma membrane (PM) protein; C-terminal palmitoylation is required for membrane anchoring and protein stability; PM localization is polarized to the daughter cell; contains a conserved, cysteine-rich palmitoylated domain (CYSPD, aka CYSTM); similarity to hydrophilins, proteins involved in the adaptive response to hyperosmotic conditions; CPP1 has a paralog, YDL012C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      270247..270633
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178364.1 → NP_009572.1  TPA: cysteine-rich palmitoylated domain-containing protein CPP1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009572.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ18, P38216
      UniProtKB/TrEMBL
      A6ZKW2, B3LNC5, C7GM36, N1P9C1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38216.1

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