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    med14 mediator complex subunit Med14 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540678, updated on 18-Sep-2024

    Summary

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    Official Symbol
    med14
    Official Full Name
    mediator complex subunit Med14
    Primary source
    PomBase:SPBC1A4.10c
    Locus tag
    SPOM_SPBC1A4.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pmc1; SPBP23A10.01c
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    Genomic context

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    See med14 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1996006..1999093, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudouridine synthase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ACN9 family protein Neighboring gene V-ATPase assembly factor Pkr1 Neighboring gene anaphase-promoting complex cullin family subunit Apc2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a fission yeast P(5)-type ATPase homologue that is essential for Ca(2+)/Mn(2+ )homeostasis in the absence of P(2)-type ATPases. Furune T, et al. Genes Genet Syst, 2008 Oct. PMID 19168988
    2. A chromatin-remodeling protein is a component of fission yeast mediator. Khorosjutina O, et al. J Biol Chem, 2010 Sep 24. PMID 20622008, Free PMC Article
    3. Fission yeast TOR signaling is essential for the down-regulation of a hyperactivated stress-response MAP kinase under salt stress. Ishiguro J, et al. Mol Genet Genomics, 2013 Feb. PMID 23271606
    4. Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Spåhr H, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572939, Free PMC Article
    5. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med14

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1996006..1999093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021716.4 → NP_595813.2  mediator complex subunit Med14 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595813.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74344, Q9P7Y4
      Conserved Domains (1) summary
      pfam08638
      Location:13 → 203
      Med14; Mediator complex subunit MED14
    Nucleotide Protein
    Heading Accession and Version

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