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    fis1 protein Fis1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539939, updated on 18-Sep-2024

    Summary

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    Official Symbol
    fis1
    Official Full Name
    protein Fis1
    Primary source
    PomBase:SPBC11G11.01
    Locus tag
    SPOM_SPBC11G11.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See fis1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1757460..1759229)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene prefoldin subunit 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene actin cortical patch component End3 Neighboring gene mRNA turnover and ribosome assembly protein Mrt4 Neighboring gene ncRNA Neighboring gene TRAPP complex subunit Trs20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission. He J, et al. PLoS Biol, 2023 Aug. PMID 37590302, Free PMC Article
    2. Loss of Msp1p in Schizosaccharomyces pombe induces a ROS-dependent nuclear mutator phenotype that affects mitochondrial fission genes. Delerue T, et al. FEBS Lett, 2016 Oct. PMID 27664110
    3. Global coordination of transcriptional control and mRNA decay during cellular differentiation. Amorim MJ, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531409, Free PMC Article
    4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-membrane adaptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial membrane fission ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in peroxisome fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasmic side of mitochondrial outer membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein Fis1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1757460..1759229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021617.4 → NP_595719.1  protein Fis1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595719.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USZ8
      Conserved Domains (3) summary
      sd00006
      Location:79 → 107
      TPR; TPR repeat [structural motif]
      cd12212
      Location:19 → 130
      Fis1; Mitochondrial Fission Protein Fis1, cytosolic domain
      pfam13432
      Location:44 → 112
      TPR_16; Tetratricopeptide repeat
    Nucleotide Protein
    Heading Accession and Version

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