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    med10 mediator complex subunit Med10 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540272, updated on 14-Nov-2024

    Summary

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    Official Symbol
    med10
    Official Full Name
    mediator complex subunit Med10
    Primary source
    PomBase:SPBC31F10.09c
    Locus tag
    SPOM_SPBC31F10.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    nut2
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    Genomic context

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    See med10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3764524..3766393, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene protein mug37 Neighboring gene ADP-ribosylation factor Sar1 Neighboring gene ncRNA Neighboring gene protein lsb5 Neighboring gene protein Mde2 Neighboring gene ncRNA Neighboring gene armadillo-type fold protein, zf-MYND type zinc finger protein, Mub1-Rad6-Ubr2 ubiquitin ligase complex Mub1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Spåhr H, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572939, Free PMC Article
    2. A genetic screen for functional partners of condensin in fission yeast. Robellet X, et al. G3 (Bethesda), 2014 Feb 19. PMID 24362309, Free PMC Article
    3. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
    4. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
    5. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med10

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3764524..3766393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022492.3 → NP_596571.2  mediator complex subunit Med10 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596571.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87310
      Conserved Domains (1) summary
      pfam09748
      Location:15 → 132
      Med10; Transcription factor subunit Med10 of Mediator complex
    Nucleotide Protein
    Heading Accession and Version

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