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    cyp3 cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540198, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cyp3
    Official Full Name
    cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp3
    Primary source
    PomBase:SPBC1709.04c
    Locus tag
    SPOM_SPBC1709.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cyp3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003423.3 (1103600..1104669, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene valine--tRNA (Val) ligase Vrs1/Vas1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome-associated molecular chaperone Sks2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterisation of Schizosaccharomyces pombe cyclophilin 3, a cyclosporin A insensitive orthologue of human USA-CyP. Pemberton TJ, et al. J Chromatogr B Analyt Technol Biomed Life Sci, 2003 Mar 25. PMID 12651004
    2. Cyclophilin sensitivity to sanglifehrin A can be correlated to the same specific tryptophan residue as cyclosporin A. Pemberton TJ, et al. FEBS Lett, 2003 Dec 4. PMID 14644438
    3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1103600..1104669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021345.3 → NP_595437.1  cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595437.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74729
      Conserved Domains (1) summary
      cd01926
      Location:5 → 171
      cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...
    Nucleotide Protein
    Heading Accession and Version

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