U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mcm7 MCM complex subunit Mcm7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540630, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mcm7
    Official Full Name
    MCM complex subunit Mcm7
    Primary source
    PomBase:SPBC25D12.03c
    Locus tag
    SPOM_SPBC25D12.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mcm7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3717577..3720039, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pescadillo-family ribosome biogenesis protein Neighboring gene ncRNA Neighboring gene nucleolar protein Dnt1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribonucleotide reductase small subunit Suc22

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7. Xu M, et al. BMC Biochem, 2013 Feb 27. PMID 23444842, Free PMC Article
    2. Redundant control of rereplication in fission yeast. Gopalakrishnan V, et al. Proc Natl Acad Sci U S A, 2001 Nov 6. PMID 11606752, Free PMC Article
    3. The replicative helicases of bacteria, archaea, and eukarya can unwind RNA-DNA hybrid substrates. Shin JH, et al. J Biol Chem, 2006 Sep 15. PMID 16829518
    4. Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases. Shin JH, et al. J Biol Chem, 2003 Dec 5. PMID 12975364
    5. Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. Gregan J, et al. Mol Biol Cell, 2003 Sep. PMID 12972571, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to 3'-5' DNA/RNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables RNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to single-stranded 3'-5' DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to single-stranded DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to single-stranded RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA strand elongation involved in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA unwinding involved in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via break-induced replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication initiation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in premeiotic DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA replication preinitiation complex IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of MCM complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of MCM complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of MCM core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pre-replicative complex IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nuclear replication fork IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    MCM complex subunit Mcm7

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3717577..3720039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022466.3 → NP_596545.1  MCM complex subunit Mcm7 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596545.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O75001, P87302
      Conserved Domains (3) summary
      COG1241
      Location:59 → 751
      Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
      pfam14551
      Location:19 → 186
      MCM_N; MCM N-terminal domain
      cl21455
      Location:398 → 537
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.