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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853888, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000001726
    Locus tag
    YKR018C
    See related
    AllianceGenome:SGD:S000001726; FungiDB:YKR018C; VEuPathDB:YKR018C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasm and nucleus. Orthologous to several human genes including TTC39B (tetratricopeptide repeat domain 39B) and TTC39C (tetratricopeptide repeat domain 39C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (473723..475900, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Mic60p Neighboring gene E3 ubiquitin-protein ligase HEL1 Neighboring gene Irs4p Neighboring gene Vps51p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
    2. Deletion of 24 open reading frames from chromosome XI from Saccharomyces cerevisiae and phenotypic analysis of the deletants. Zúñiga S, et al. Gene, 1999 Jun 11. PMID 10375630
    3. Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins. Shyu P Jr, et al. Sci Rep, 2019 Jun 14. PMID 31201345, Free PMC Article
    4. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
    5. Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions. Hill SM, et al. Cell Rep, 2016 Jul 19. PMID 27373154, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_012943.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress; YKR018C has a paralog, IML2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      473723..475900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179808.1 → NP_012943.1  TPA: uncharacterized protein YKR018C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012943.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX83, P36114
      UniProtKB/TrEMBL
      C7GNP1, G2WI49, N1P0G5
      Conserved Domains (1) summary
      pfam10300
      Location:36 → 629
      DUF3808; Protein of unknown function (DUF3808)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36114.1

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