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    spo6 Spo4-Spo6 kinase complex regulatory subunit Spo6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540044, updated on 18-Sep-2024

    Summary

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    Official Symbol
    spo6
    Official Full Name
    Spo4-Spo6 kinase complex regulatory subunit Spo6
    Primary source
    PomBase:SPBC1778.04
    Locus tag
    SPOM_SPBC1778.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spo6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (3103097..3104941)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene telomere-binding protein Rap1 Neighboring gene NADH pyrophosphatase Neighboring gene guanyl-nucleotide exchange factor Lam2 Neighboring gene ncRNA Neighboring gene fimbrin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Schizosaccharomyces pombe spo6+ gene encoding a nuclear protein with sequence similarity to budding yeast Dbf4 is required for meiotic second division and sporulation. Nakamura T, et al. Genes Cells, 2000 Jun. PMID 10886372
    2. A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe. Kovacikova I, et al. Cell Cycle, 2013 Feb 15. PMID 23370392, Free PMC Article
    3. Novel fission yeast Cdc7-Dbf4-like kinase complex required for the initiation and progression of meiotic second division. Nakamura T, et al. Mol Cell Biol, 2002 Jan. PMID 11739743, Free PMC Article
    4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiosis II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Spo4-Spo6 kinase complex regulatory subunit Spo6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3103097..3104941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022209.3 → NP_596287.1  Spo4-Spo6 kinase complex regulatory subunit Spo6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596287.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y7J1
      Conserved Domains (4) summary
      smart00586
      Location:421 → 469
      ZnF_DBF; Zinc finger in DBF-like proteins
      COG5067
      Location:7 → 471
      DBF4; Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning]
      cd00027
      Location:130 → 180
      BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
      pfam08630
      Location:183 → 296
      Dfp1_Him1_M; Dfp1/Him1, central region
    Nucleotide Protein
    Heading Accession and Version

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