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    scr1 DNA-binding transcription repressor, glucose sensing, Scr1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540768, updated on 18-Sep-2024

    Summary

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    Official Symbol
    scr1
    Official Full Name
    DNA-binding transcription repressor, glucose sensing, Scr1
    Primary source
    PomBase:SPBC1D7.02c
    Locus tag
    SPOM_SPBC1D7.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC1D7.02
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    Genomic context

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    See scr1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1752093..1755619)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene prefoldin subunit 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe. Tanaka N, et al. Biochem Biophys Res Commun, 1998 Apr 7. PMID 9535817
    2. Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress. Schutt KL, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515144, Free PMC Article
    3. Snf1-like protein kinase Ssp2 regulates glucose derepression in Schizosaccharomyces pombe. Matsuzawa T, et al. Eukaryot Cell, 2012 Feb. PMID 22140232, Free PMC Article
    4. Genetic-interaction screens uncover novel biological roles and regulators of transcription factors in fission yeast. Chatfield-Reed K, et al. G3 (Bethesda), 2022 Aug 25. PMID 35924983, Free PMC Article
    5. The gld1+ gene encoding glycerol dehydrogenase is required for glycerol metabolism in Schizosaccharomyces pombe. Matsuzawa T, et al. Appl Microbiol Biotechnol, 2010 Jun. PMID 20396879

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbon catabolite repression of transcription from RNA polymerase II promoter by glucose IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of flocculation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleoplasm EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding transcription repressor, glucose sensing, Scr1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1752093..1755619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021615.3 → NP_595717.1  DNA-binding transcription repressor, glucose sensing, Scr1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595717.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14335
      Conserved Domains (4) summary
      COG5048
      Location:1 → 478
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:28 → 48
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:26 → 48
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:43 → 67
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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