U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pdk1 serine/threonine protein kinase Ppk21/Pdk1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539807, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pdk1
    Official Full Name
    serine/threonine protein kinase Ppk21/Pdk1
    Primary source
    PomBase:SPBC1778.10c
    Locus tag
    SPOM_SPBC1778.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ppk21; SPBC4C3.11
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See pdk1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (3114231..3116509, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GTPase-activating protein Neighboring gene ARP2/3 actin-organizing complex subunit Arc21 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene proteasome core particle subunit beta 1 Pre3 Neighboring gene ncRNA Neighboring gene alpha-1,3-galactosyltransferase Otg3

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phosphoinositide-Dependent Protein Kinases Regulate Cell Cycle Progression Through the SAD Kinase Cdr2 in Fission Yeast. Liu K, et al. Front Microbiol, 2021. PMID 35082773, Free PMC Article
    2. Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesis. Bimbó A, et al. Mol Biol Cell, 2005 Jul. PMID 15857958, Free PMC Article
    3. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
    4. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of attachment of mitotic spindle microtubules to kinetochore IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of mitotic division septum assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sphingolipid mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in medial cortical node IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine protein kinase Ppk21/Pdk1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3114231..3116509 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355802.2 → NP_001342881.1  serine/threonine protein kinase Ppk21/Pdk1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43064, Q9Y7J6
      Conserved Domains (1) summary
      cd05581
      Location:54 → 315
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.