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    epl1 NuA4 histone acetyltransferase core complex-Piccolo HAT module linker protein Epl1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539428, updated on 18-Sep-2024

    Summary

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    Official Symbol
    epl1
    Official Full Name
    NuA4 histone acetyltransferase core complex-Piccolo HAT module linker protein Epl1
    Primary source
    PomBase:SPCC830.05c
    Locus tag
    SPOM_SPCC830.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See epl1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (2188083..2190875, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene polynucleotide kinase Grc3 Neighboring gene protein mug128 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene calcineurin regulatory subunit B Neighboring gene ncRNA Neighboring gene DNAJ domain-containing protein Psi1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The structure of the NuA4-Tip60 complex reveals the mechanism and importance of long-range chromatin modification. Fréchard A, et al. Nat Struct Mol Biol, 2023 Sep. PMID 37550452
    2. Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast. Elías-Villalobos A, et al. Nat Commun, 2019 Nov 20. PMID 31748520, Free PMC Article
    3. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article
    4. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Shevchenko A, et al. Genome Biol, 2008. PMID 19040720, Free PMC Article
    5. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair-dependent chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of piccolo histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NuA4 histone acetyltransferase core complex-Piccolo HAT module linker protein Epl1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2188083..2190875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023466.3 → NP_588475.1  NuA4 histone acetyltransferase core complex-Piccolo HAT module linker protein Epl1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588475.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UU94
      Conserved Domains (1) summary
      pfam10513
      Location:12 → 159
      EPL1; Enhancer of polycomb-like
    Nucleotide Protein
    Heading Accession and Version

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