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    MRPL10 mitochondrial 54S ribosomal protein YmL10/YmL18 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRPL10
    Official Full Name
    mitochondrial 54S ribosomal protein YmL10/YmL18
    Primary source
    SGD:S000005228
    Locus tag
    YNL284C
    See related
    AllianceGenome:SGD:S000005228; FungiDB:YNL284C; VEuPathDB:YNL284C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MRPL18; uL15m
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL15 (mitochondrial ribosomal protein L15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRPL10 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (103134..104102, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene gag-pol fusion protein Neighboring gene gag protein Neighboring gene tRNA-Asn Neighboring gene tRNA-Thr Neighboring gene Wsc2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    2. The yeast protein Mam33 functions in the assembly of the mitochondrial ribosome. Hillman GA, et al. J Biol Chem, 2019 Jun 21. PMID 31053642, Free PMC Article
    3. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article
    4. The Rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast. Imbeault D, et al. J Biol Chem, 2008 Oct 10. PMID 18708354
    5. Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. Frazier AE, et al. J Cell Biol, 2006 Feb 13. PMID 16476776, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL10/YmL18
    NP_014115.1
    • Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      103134..104102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183122.1 → NP_014115.1  TPA: mitochondrial 54S ribosomal protein YmL10/YmL18 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014115.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0R0, P36520, P36524
      UniProtKB/TrEMBL
      A6ZRG1, B3LPC3, B5VQD2, C7GP80, C8ZGN7, G2WLI2, N1NWX0
      Conserved Domains (1) summary
      TIGR01071
      Location:60 → 211
      rplO_bact; ribosomal protein L15, bacterial/organelle
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36520.2

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