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    SEG2 Seg2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853756, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SEG2
    Official Full Name
    Seg2p
    Primary source
    SGD:S000001588
    Locus tag
    YKL105C
    See related
    AllianceGenome:SGD:S000001588; FungiDB:YKL105C; VEuPathDB:YKL105C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cell periphery. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SEG2 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (239185..242583, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene aspartate transaminase AAT1 Neighboring gene glutamine--fructose-6-phosphate transaminase (isomerizing) GFA1 Neighboring gene uncharacterized protein Neighboring gene metalloaminopeptidase APE1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Formation and stability of eisosomes in the filamentous fungus Ashbya gossypii. Seger S, et al. J Cell Sci, 2011 May 15. PMID 21525038
    2. Molecular evolution of minisatellites in hemiascomycetous yeasts. Richard GF, et al. Mol Biol Evol, 2006 Jan. PMID 16177231
    3. Seg1 controls eisosome assembly and shape. Moreira KE, et al. J Cell Biol, 2012 Aug 6. PMID 22869600, Free PMC Article
    4. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Fröhlich F, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057013, Free PMC Article
    5. Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation. Bedard LG, et al. J Biol Chem, 2016 Jun 24. PMID 27143358, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Seg2p
    NP_012817.1
    • Eisosome component; likely plays only a minor role in eisosome assembly; shown to interact with Seg1p by affinity purification and mass spec; SWAT-GFP and mCherry fusion proteins localize to the cell periphery; similar to A. gossypii SEG gene which is important for stabilizing eisosomes; SEG2 has a paralog, SEG1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      239185..242583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179671.1 → NP_012817.1  TPA: Seg2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012817.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXI3, P34250
      UniProtKB/TrEMBL
      A6ZZL2, G2WHS9
      Conserved Domains (1) summary
      PRK03918
      Location:293 → 383
      PRK03918; DNA double-strand break repair ATPase Rad50
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34250.1

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