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    ell1 RNA polymerase II transcription elongation factor Ell1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541257, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ell1
    Official Full Name
    RNA polymerase II transcription elongation factor Ell1
    Primary source
    PomBase:SPBP23A10.14c
    Locus tag
    SPOM_SPBP23A10.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ell1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (2028610..2031140, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FRG1 family mRNA-processing protein Neighboring gene origin recognition complex subunit Orc4 Neighboring gene ncRNA Neighboring gene tRNA-Asn

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional interaction between ELL transcription elongation factor and Epe1 reveals the role of Epe1 in the regulation of transcription outside heterochromatin. Sweta K, et al. Mol Microbiol, 2021 Jul. PMID 33533152
    2. The amino-terminal domain of ELL transcription elongation factor is essential for ELL function in Schizosaccharomyces pombe. Sweta K, et al. Microbiology (Reading), 2017 Nov. PMID 29043956
    3. Structure function characterization of the ELL Associated Factor (EAF) from Schizosaccharomyces pombe. Dabas P, et al. Gene, 2018 Jan 30. PMID 29032152
    4. Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex. Gopalan S, et al. Nucleic Acids Res, 2018 Nov 2. PMID 30102332, Free PMC Article
    5. Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. Banks CA, et al. J Biol Chem, 2007 Feb 23. PMID 17150956

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional interaction between ELL transcription elongation factor and Epe1 reveals the role of Epe1 in the regulation of transcription outside heterochromatin.
      Title: Functional interaction between ELL transcription elongation factor and Epe1 reveals the role of Epe1 in the regulation of transcription outside heterochromatin.
    2. This complex includes S. pombe Ell1, Eaf1, and a previously uncharacterized protein we designate Ell1 binding protein 1 (Ebp1), which is distantly related to metazoan AFF family members. Like the metazoan SEC, this S. pombe ELL complex appears to function broadly in Pol II transcription.
      Title: Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription elongation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription elongation by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of super elongation complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA polymerase II transcription elongation factor Ell1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2028610..2031140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021730.3 → NP_595826.1  RNA polymerase II transcription elongation factor Ell1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595826.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7X2
      Conserved Domains (1) summary
      pfam10390
      Location:63 → 269
      ELL; RNA polymerase II elongation factor ELL
    Nucleotide Protein
    Heading Accession and Version

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