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    spn2 mitotic and meiotic (sporulation) septin Spn2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543513, updated on 18-Sep-2024

    Summary

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    Official Symbol
    spn2
    Official Full Name
    mitotic and meiotic (sporulation) septin Spn2
    Primary source
    PomBase:SPAC821.06
    Locus tag
    SPOM_SPAC821.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spn2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (990205..991889)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation initiation factor eIF3h (p40) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor Moc3 Neighboring gene ncRNA Neighboring gene ubiquitin ligase Slp1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of septins in the orientation of forespore membrane extension during sporulation in fission yeast. Onishi M, et al. Mol Cell Biol, 2010 Apr. PMID 20123972, Free PMC Article
    2. Requirements of fission yeast septins for complex formation, localization, and function. An H, et al. Mol Biol Cell, 2004 Dec. PMID 15385632, Free PMC Article
    3. Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex. Lei B, et al. J Cell Sci, 2014 Sep 15. PMID 25015293
    4. Rho4 interaction with exocyst and septins regulates cell separation in fission yeast. Pérez P, et al. Microbiology (Reading), 2015 May. PMID 25724972
    5. Nanoscale architecture of the Schizosaccharomyces pombe contractile ring. McDonald NA, et al. Elife, 2017 Sep 15. PMID 28914606, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton-dependent cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in septin ring assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spore membrane bending pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in mating projection septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in medial cortex septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of meiotic septin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic actomyosin contractile ring, proximal layer IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitotic septin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in prospore septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of septin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in septin ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitotic and meiotic (sporulation) septin Spn2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      990205..991889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018557.3 → NP_593159.1  mitotic and meiotic (sporulation) septin Spn2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593159.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09116, Q9UT47
      Conserved Domains (3) summary
      cd01850
      Location:29 → 303
      CDC_Septin; CDC/Septin GTPase family
      COG5019
      Location:10 → 331
      CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cl21455
      Location:5 → 49
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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