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    dea2 adenine deaminase Dea2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540066, updated on 18-Sep-2024

    Summary

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    Official Symbol
    dea2
    Official Full Name
    adenine deaminase Dea2
    Primary source
    PomBase:SPBC1198.02
    Locus tag
    SPOM_SPBC1198.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See dea2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (174816..176135)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcription factor Cha4 Neighboring gene ncRNA Neighboring gene glutathione-dependent formaldehyde dehydrogenase Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription regulator Zas1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hydrolytic cleavage of N6-substituted adenine derivatives by eukaryotic adenine and adenosine deaminases. Pospísilová H, et al. Biosci Rep, 2008 Dec. PMID 18673302
    2. Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family. Ribard C, et al. J Mol Biol, 2003 Dec 12. PMID 14643670
    3. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables adenine deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenine deaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in IMP salvage IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in adenine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in adenine catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in hypoxanthine salvage IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in hypoxanthine salvage IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    adenine deaminase Dea2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      174816..176135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020977.3 → NP_595071.1  adenine deaminase Dea2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595071.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6I7
      Conserved Domains (1) summary
      cd01320
      Location:12 → 342
      ADA; Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in ...
    Nucleotide Protein
    Heading Accession and Version

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