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    gdh2 NAD-dependent glutamate dehydrogenase Gdh2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539148, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gdh2
    Official Full Name
    NAD-dependent glutamate dehydrogenase Gdh2
    Primary source
    PomBase:SPCC132.04c
    Locus tag
    SPOM_SPCC132.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See gdh2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1332569..1336175, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Filamentous invasive growth of mutants of the genes encoding ammonia-metabolizing enzymes in the fission yeast Schizosaccharomyces pombe. Sasaki Y, et al. PLoS One, 2017. PMID 28982178, Free PMC Article
    2. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
    3. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    5. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables glutamate dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutamate dehydrogenase (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamate catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in glutamate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NAD-dependent glutamate dehydrogenase Gdh2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1332569..1336175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023138.3 → NP_588149.1  NAD-dependent glutamate dehydrogenase Gdh2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588149.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USN5
      Conserved Domains (4) summary
      smart00839
      Location:872 → 979
      ELFV_dehydrog; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
      PTZ00324
      Location:87 → 1105
      PTZ00324; glutamate dehydrogenase 2; Provisional
      cl21454
      Location:740 → 1006
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
      cl22883
      Location:556 → 655
      Bac_GDH; Bacterial NAD-glutamate dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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