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    dld1 dihydrolipoamide dehydrogenase Dld1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543269, updated on 14-Nov-2024

    Summary

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    Official Symbol
    dld1
    Official Full Name
    dihydrolipoamide dehydrogenase Dld1
    Primary source
    PomBase:SPAC1002.09c
    Locus tag
    SPOM_SPAC1002.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    dldh
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    Genomic context

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    See dld1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1811408..1813740, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase Ats1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase-specificity factor Mtf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene snRNP binding protein Sgt1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GPI-anchor transamidase complex subunit Gaa1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    2. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables dihydrolipoyl dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dihydrolipoyl dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in 2-oxoglutarate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in acetyl-CoA biosynthetic process from pyruvate ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in aerobic respiration IC
    Inferred by Curator
    more info
    		  
    involved_in glycine decarboxylation via glycine cleavage system ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in pyruvate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of glycine cleavage complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrial matrix IC
    Inferred by Curator
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of oxoglutarate dehydrogenase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of pyruvate dehydrogenase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    dihydrolipoamide dehydrogenase Dld1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1811408..1813740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018930.3 → NP_593496.1  dihydrolipoamide dehydrogenase Dld1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593496.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O00087, Q9US50
      Conserved Domains (4) summary
      PRK06327
      Location:45 → 511
      PRK06327; dihydrolipoamide dehydrogenase; Validated
      pfam00070
      Location:219 → 297
      Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
      pfam02852
      Location:392 → 498
      Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
      pfam13450
      Location:50 → 84
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
    Nucleotide Protein
    Heading Accession and Version

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