U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rfc1 DNA replication factor C complex subunit Rfc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540426, updated on 14-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rfc1
    Official Full Name
    DNA replication factor C complex subunit Rfc1
    Primary source
    PomBase:SPBC23E6.07c
    Locus tag
    SPOM_SPBC23E6.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rfc1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (3852657..3856022, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribosomal export complex protein Arx1 Neighboring gene ncRNA Neighboring gene 3,4-dihydroxy-2-butanone 4-phosphate synthase Neighboring gene ncRNA Neighboring gene protein sat1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures. Kai M, et al. Mol Cell Biol, 2001 May. PMID 11313455, Free PMC Article
    2. Critical Function of γH2A in S-Phase. Mejia-Ramirez E, et al. PLoS Genet, 2015 Sep. PMID 26368543, Free PMC Article
    3. Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast. Kim J, et al. Nucleic Acids Res, 2005. PMID 16040599, Free PMC Article
    4. Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion. Tanaka H, et al. Mol Cell Biol, 1999 Feb. PMID 9891039, Free PMC Article
    5. Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe. Chen X, et al. J Biol Chem, 2000 Jun 9. PMID 10748208

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity NAS
    Non-traceable Author Statement
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to DNA clamp loader activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA strand elongation involved in mitotic DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in UV-damage excision repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic DNA replication leading strand elongation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromatin IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of nuclear DNA replication factor C complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA replication factor C complex subunit Rfc1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3852657..3856022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022528.3 → NP_596607.1  DNA replication factor C complex subunit Rfc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596607.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60182, Q9US97
      Conserved Domains (7) summary
      cd00009
      Location:409 → 539
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      smart00382
      Location:412 → 542
      AAA; ATPases associated with a variety of cellular activities
      COG0470
      Location:506 → 590
      HolB; DNA polymerase III, delta prime subunit [Replication, recombination and repair]
      COG5275
      Location:78 → 360
      COG5275; BRCT domain type II [General function prediction only]
      cd00027
      Location:243 → 313
      BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
      pfam08519
      Location:689 → 843
      RFC1; Replication factor RFC1 C terminal domain
      pfam12767
      Location:541 → 581
      SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.