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    las1 rixosome complex/ Las1 complex endonuclease Las1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540034, updated on 18-Sep-2024

    Summary

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    Official Symbol
    las1
    Official Full Name
    rixosome complex/ Las1 complex endonuclease Las1
    Primary source
    PomBase:SPBC16C6.12c
    Locus tag
    SPOM_SPBC16C6.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See las1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4352543..4354110, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L32 Neighboring gene ncRNA Neighboring gene coatomer beta' subunit protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Thoms M, et al. EMBO Rep, 2023 Dec 6. PMID 37921038, Free PMC Article
    2. Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing. Kitano E, et al. J Biol Chem, 2011 Apr 29. PMID 21385875, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IC
    Inferred by Curator
    more info
    		  
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Las1 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear envelope HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of rixosome complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rixosome complex/ Las1 complex endonuclease Las1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4352543..4354110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023831.3 → NP_596810.1  rixosome complex/ Las1 complex endonuclease Las1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596810.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42936
      Conserved Domains (1) summary
      pfam04031
      Location:6 → 149
      Las1; Las1-like
    Nucleotide Protein
    Heading Accession and Version

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