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    tpp1 trehalose-6-phosphate phosphatase Tpp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542577, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tpp1
    Official Full Name
    trehalose-6-phosphate phosphatase Tpp1
    Primary source
    PomBase:SPAC19G12.15c
    Locus tag
    SPOM_SPAC19G12.15C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tpp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4074998..4077857, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 1-phosphatidylinositol-4-phosphate 5-kinase Its3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein adg2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe. Soto T, et al. Eur J Biochem, 2002 Aug. PMID 12153582
    2. Characterization of tpp1(+) as encoding a main trehalose-6P phosphatase in the fission yeast Schizosaccharomyces pombe. Franco A, et al. J Bacteriol, 2000 Oct. PMID 11004189, Free PMC Article
    3. Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe. Soto T, et al. Eur J Biochem, 2002 Oct. PMID 12383265
    4. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
    5. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables trehalose-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables trehalose-phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in trehalose biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in trehalose metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in trehalose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in trehalose metabolism in response to stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose metabolism in response to stress NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trehalose-6-phosphate phosphatase Tpp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4074998..4077857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019859.3 → NP_594430.1  trehalose-6-phosphate phosphatase Tpp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594430.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78875, Q8TGH5
      Conserved Domains (4) summary
      cd03788
      Location:38 → 535
      GT1_TPS; Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a ...
      COG1877
      Location:547 → 817
      OtsB; Trehalose-6-phosphatase [Carbohydrate transport and metabolism]
      pfam00982
      Location:31 → 536
      Glyco_transf_20; Glycosyltransferase family 20
      pfam02358
      Location:568 → 803
      Trehalose_PPase; Trehalose-phosphatase
    Nucleotide Protein
    Heading Accession and Version

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