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    IES5 Ies5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856827, updated on 9-Dec-2024

    Summary

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    Official Symbol
    IES5
    Official Full Name
    Ies5p
    Primary source
    SGD:S000000894
    Locus tag
    YER092W
    See related
    AllianceGenome:SGD:S000000894; FungiDB:YER092W; VEuPathDB:YER092W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in telomere maintenance via recombination. Located in nucleus. Part of Ino80 complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See IES5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (342855..343232)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene anthranilate synthase TRP2 Neighboring gene 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase Neighboring gene TORC2 complex subunit TSC11 Neighboring gene Aim11p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The INO80 Complex Removes H2A.Z to Promote Presynaptic Filament Formation during Homologous Recombination. Lademann CA, et al. Cell Rep, 2017 May 16. PMID 28514650
    2. The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Chambers AL, et al. Genes Dev, 2012 Dec 1. PMID 23207916, Free PMC Article
    3. ATP-dependent chromatin remodeling shapes the DNA replication landscape. Vincent JA, et al. Nat Struct Mol Biol, 2008 May. PMID 18408730, Free PMC Article
    4. The INO80 Complex Requires the Arp5-Ies6 Subcomplex for Chromatin Remodeling and Metabolic Regulation. Yao W, et al. Mol Cell Biol, 2016 Jan 11. PMID 26755556, Free PMC Article
    5. Identification of Topological Network Modules in Perturbed Protein Interaction Networks. Sardiu ME, et al. Sci Rep, 2017 Mar 8. PMID 28272416, Free PMC Article

    See all (80) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in telomere maintenance via recombination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ino80 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Ino80 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ies5p
    NP_011017.3
    • Non-essential INO80 chromatin remodeling complex subunit; deletion affects telomere maintenance via recombination

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      342855..343232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178983.3 → NP_011017.3  TPA: Ies5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011017.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLZ9, P40060
      UniProtKB/TrEMBL
      A6ZR48, B3LRL0, C7GRS5, C8Z7B0, G2WCY3, N1P585
      Conserved Domains (1) summary
      pfam17335
      Location:11 → 123
      IES5; Ino80 complex subunit 5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40060.1

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