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    lsm3 U6 snRNP-associated protein Lsm3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540212, updated on 18-Sep-2024

    Summary

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    Official Symbol
    lsm3
    Official Full Name
    U6 snRNP-associated protein Lsm3
    Primary source
    PomBase:SPBC9B6.05c
    Locus tag
    SPOM_SPBC9B6.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See lsm3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (1821460..1822728, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene zf-FYVE type zinc finger protein and glutamine sensor Pib2 Neighboring gene ncRNA Neighboring gene translation elongation factor EF-Tu Tuf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL15m Neighboring gene Nop52 family nucleolar protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Hu X, et al. Cell Rep, 2020 Dec 29. PMID 33378677
    2. LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast. Mennie AK, et al. Nat Commun, 2018 Feb 8. PMID 29422503, Free PMC Article
    3. Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe. Wu D, et al. PLoS One, 2012. PMID 22615807, Free PMC Article
    4. Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Montemayor EJ, et al. RNA, 2020 Oct. PMID 32518066, Free PMC Article
    5. LARP7 family proteins have conserved function in telomerase assembly. Collopy LC, et al. Nat Commun, 2018 Feb 8. PMID 29422501, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA folding chaperone EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables U2 snRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to poly(U) RNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables telomerase RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Lsm1-7-Pat1 complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of Lsm1-7-Pat1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Lsm2-8 complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2 snRNP EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U6 snRNP EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of U6 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in chromosome, telomeric repeat region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of telomerase holoenzyme complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    U6 snRNP-associated protein Lsm3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1821460..1822728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021647.3 → NP_595747.1  U6 snRNP-associated protein Lsm3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595747.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y7M4
      Conserved Domains (1) summary
      cd01730
      Location:9 → 90
      LSm3; Like-Sm protein 3
    Nucleotide Protein
    Heading Accession and Version

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