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    alg11 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase Alg11 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539054, updated on 18-Sep-2024

    Summary

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    Official Symbol
    alg11
    Official Full Name
    GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase Alg11
    Primary source
    PomBase:SPCC330.08
    Locus tag
    SPOM_SPCC330.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    gmd3
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    Genomic context

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    See alg11 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (124266..127134)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA processing protein Enp2 Neighboring gene ncRNA Neighboring gene mRNA 5'-cap (guanine-N7-)-methyltransferase Pcm1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe gmd3(+)/alg11(+) is a functional homologue of Saccharomyces cerevisiae ALG11 which is involved in N-linked oligosaccharide synthesis. Umeda K, et al. Yeast, 2000 Oct. PMID 11015724
    2. The dolichol pathway of N-linked glycosylation. Burda P, et al. Biochim Biophys Acta, 1999 Jan 6. PMID 9878760
    3. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    4. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dolichol-linked oligosaccharide biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic side of endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase Alg11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      124266..127134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022703.3 → NP_587708.1  GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase Alg11 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587708.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74878
      Conserved Domains (2) summary
      cd03806
      Location:55 → 455
      GT1_ALG11_like; This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown ...
      PLN02949
      Location:54 → 456
      PLN02949; transferase, transferring glycosyl groups
    Nucleotide Protein
    Heading Accession and Version

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