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    FIG1 Fig1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852328, updated on 9-Dec-2024

    Summary

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    Official Symbol
    FIG1
    Official Full Name
    Fig1p
    Primary source
    SGD:S000000244
    Locus tag
    YBR040W
    See related
    AllianceGenome:SGD:S000000244; FungiDB:YBR040W; VEuPathDB:YBR040W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cell morphogenesis involved in conjugation with cellular fusion and cytogamy. Located in fungal-type cell wall and mating projection tip. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See FIG1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (316968..317864)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene chitin synthase CHS2 Neighboring gene F1F0 ATP synthase subunit gamma Neighboring gene long-chain fatty acid transporter FAT1 Neighboring gene putative acyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast mating. Aguilar PS, et al. Mol Biol Cell, 2007 Feb. PMID 17151357, Free PMC Article
    2. Construction of a novel detection system for protein-protein interactions using yeast G-protein signaling. Fukuda N, et al. FEBS J, 2009 May. PMID 19476500
    3. Glucose-induced calcium influx in budding yeast involves a novel calcium transport system and can activate calcineurin. Groppi S, et al. Cell Calcium, 2011 Jun. PMID 21511333
    4. Sexual pheromone modulates the frequency of cytosolic Ca(2+) bursts in Saccharomyces cerevisiae. Carbó N, et al. Mol Biol Cell, 2017 Feb 15. PMID 28031257, Free PMC Article
    5. Pheromone-regulated genes required for yeast mating differentiation. Erdman S, et al. J Cell Biol, 1998 Feb 9. PMID 9456310, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell morphogenesis involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in conjugation with cellular fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytogamy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    is_active_in mating projection tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mating projection tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fig1p
    NP_009596.1
    • Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating; targeted to vacuole via AP-3 pathway

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      316968..317864
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178388.1 → NP_009596.1  TPA: Fig1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009596.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ40, P38224, Q70DD9, Q70DE0, Q70DE1, Q70DE3, Q70DE4, Q70DE5, Q70DE6
      UniProtKB/TrEMBL
      A6ZKY4, B3LNA5, D3UED6, G2W945
      Conserved Domains (1) summary
      pfam12351
      Location:67 → 262
      Fig1; Ca2+ regulator and membrane fusion protein Fig1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38224.1

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