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    Ahnak2 AHNAK nucleoprotein 2 [ Mus musculus (house mouse) ]

    Gene ID: 100041194, updated on 4-Jan-2025

    Summary

    Official Symbol
    Ahnak2provided by MGI
    Official Full Name
    AHNAK nucleoprotein 2provided by MGI
    Primary source
    MGI:MGI:2144831
    See related
    Ensembl:ENSMUSG00000118667 AllianceGenome:MGI:2144831
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm72; Gm1185
    Summary
    Predicted to be involved in regulation of RNA splicing. Predicted to be located in cytosol and plasma membrane. Predicted to be active in costamere and nucleus. Is expressed in dorsal root ganglion and trigeminal ganglion. Orthologous to human AHNAK2 (AHNAK nucleoprotein 2). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in ovary adult (RPKM 46.7), colon adult (RPKM 40.7) and 13 other tissues See more
    Orthologs
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    Genomic context

    See Ahnak2 in Genome Data Viewer
    Location:
    12 F1; 12 61.2 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112738631..112766278, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112772197..112802658, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 11 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5361 Neighboring gene phospholipase D family member 4 Neighboring gene clathrin binding box of aftiphilin containing 1 Neighboring gene STARR-seq mESC enhancer starr_33365 Neighboring gene cell division cycle associated 4 Neighboring gene STARR-seq mESC enhancer starr_33367 Neighboring gene predicted gene, 52009

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    General gene information

    Clone Names

    • MGC170093, MGC170094

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of RNA splicing  
    Component Evidence Code Pubs
    is_active_in costamere  
    is_active_in cytoplasm  
    located_in cytosol  
    is_active_in nucleus  
    located_in plasma membrane  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378498.1NP_001365427.1  protein AHNAK2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      MF597757
      UniProtKB/TrEMBL
      A0A7N9VR94
      Related
      ENSMUSP00000159404.2, ENSMUST00000239525.1
      Conserved Domains (1) summary
      cd00992
      Location:108187
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. NM_001378499.1NP_001365428.1  protein AHNAK2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      MF597757
      Conserved Domains (1) summary
      cd00992
      Location:988
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      112738631..112766278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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