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    Ubqln5 ubiquilin 5 [ Mus musculus (house mouse) ]

    Gene ID: 70980, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ubqln5provided by MGI
    Official Full Name
    ubiquilin 5provided by MGI
    Primary source
    MGI:MGI:1918230
    See related
    Ensembl:ENSMUSG00000055643 AllianceGenome:MGI:1918230
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4931431F19Rik
    Summary
    Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Located in mitochondrion. Is expressed in olfactory epithelium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Ubqln5 in Genome Data Viewer
    Location:
    7 E3; 7 54.85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (103777120..103779030, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (104127913..104129823, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 51 subfamily A member 24 Neighboring gene olfactory receptor family 52 subfamily D member 1 Neighboring gene STARR-seq mESC enhancer starr_19730 Neighboring gene ubiquilin 3 Neighboring gene ubiquilin-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ubiquilin gene family: evolutionary patterns and functional insights. Marín I. BMC Evol Biol, 2014 Mar 28. PMID 24674348, Free PMC Article
    2. CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Lu Y, et al. Biol Reprod, 2019 Aug 1. PMID 31201419, Free PMC Article
    3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables polyubiquitin modification-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    ubiquilin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027634.1 → NP_081910.1  ubiquilin-3

      See identical proteins and their annotated locations for NP_081910.1

      Status: VALIDATED

      Source sequence(s)
      AK016497
      Consensus CDS
      CCDS52341.1
      UniProtKB/TrEMBL
      Q9D4I8
      Related
      ENSMUSP00000062054.5, ENSMUST00000053743.6
      Conserved Domains (3) summary
      smart00213
      Location:24 → 94
      UBQ; Ubiquitin homologues
      cd14399
      Location:467 → 506
      UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins
      cl00155
      Location:24 → 94
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      103777120..103779030 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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