U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Gng13 guanine nucleotide binding protein (G protein), gamma 13 [ Mus musculus (house mouse) ]

    Gene ID: 64337, updated on 27-Nov-2024

    Summary

    Official Symbol
    Gng13provided by MGI
    Official Full Name
    guanine nucleotide binding protein (G protein), gamma 13provided by MGI
    Primary source
    MGI:MGI:1925616
    See related
    Ensembl:ENSMUSG00000025739 AllianceGenome:MGI:1925616
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hg3j; Ggamma13; 1500031D04Rik
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway and sensory perception of taste. Located in dendrite. Part of heterotrimeric G-protein complex. Is active in synapse. Is expressed in brain; gonad; gut; and liver. Orthologous to human GNG13 (G protein subunit gamma 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 73.0), cortex adult (RPKM 33.6) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gng13 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.82 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (25936146..25938076)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25717172..25719102)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930541O19 gene Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene CTF18, chromosome transmission fidelity factor 18 Neighboring gene STARR-positive B cell enhancer ABC_E3190 Neighboring gene RNA pseudouridylate synthase domain containing 1 Neighboring gene mesothelin-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta-subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables G-protein beta-subunit binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of heterotrimeric G-protein complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
    Names
    heterotrimeric guanine nucleotide-binding protein 3j

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357782.1NP_001344711.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13

      Status: VALIDATED

      Source sequence(s)
      AC134908, EH103048
      Consensus CDS
      CCDS37503.1
      UniProtKB/Swiss-Prot
      Q9JMF3
      Related
      ENSMUSP00000110760.4, ENSMUST00000115108.4
      Conserved Domains (1) summary
      cd00068
      Location:661
      GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
    2. NM_022422.5NP_071867.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13

      See identical proteins and their annotated locations for NP_071867.1

      Status: VALIDATED

      Source sequence(s)
      BU554843, EH103048
      Consensus CDS
      CCDS37503.1
      UniProtKB/Swiss-Prot
      Q9JMF3
      Related
      ENSMUSP00000131648.2, ENSMUST00000172002.8
      Conserved Domains (1) summary
      cd00068
      Location:661
      GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      25936146..25938076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)