U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG8578 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32540, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG8578provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030699
    Locus tag
    Dmel_CG8578
    See related
    AllianceGenome:FB:FBgn0030699
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8578
    Summary
    Enables small GTPase binding activity. Involved in adult somatic muscle development. Orthologous to several human genes including LRRFIP2 (LRR binding FLII interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG8578 in Genome Data Viewer
    Location:
    13F10-13F12; 1-52 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15844476..15847858)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15738509..15741891)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Arginyl-tRNA synthetase Neighboring gene stunted Neighboring gene Ubiquitin like 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions. Kidd T, et al. Genetics, 2005 Jun. PMID 15834145, Free PMC Article
    2. Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression. Dyer JO, et al. J Mol Biol, 2017 Jun 30. PMID 27984043, Free PMC Article
    3. A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Thomae AW, et al. Dev Cell, 2013 Nov 25. PMID 24239514
    4. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article
    5. Toward a comprehensive map of the effectors of rab GTPases. Gillingham AK, et al. Dev Cell, 2014 Nov 10. PMID 25453831, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adult somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG8578-PA
    CG8578-PB
    CG8578-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15844476..15847858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298374.1 → NP_001285303.1  uncharacterized protein Dmel_CG8578, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0E4, Q9VXN3
      Conserved Domains (1) summary
      pfam09738
      Location:47 → 321
      DUF2051; Double stranded RNA binding protein (DUF2051)

    2. NM_132854.3 → NP_573082.1  uncharacterized protein Dmel_CG8578, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573082.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0E4, Q9VXN3
      Related
      FBpp0073918
      Conserved Domains (1) summary
      pfam09738
      Location:47 → 321
      DUF2051; Double stranded RNA binding protein (DUF2051)

    3. NM_001298373.1 → NP_001285302.1  uncharacterized protein Dmel_CG8578, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285302.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0E4, Q9VXN3
      Conserved Domains (1) summary
      pfam09738
      Location:47 → 321
      DUF2051; Double stranded RNA binding protein (DUF2051)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXN3 Q9VXN3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools