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    CG8565 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32538, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8565provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030697
    Locus tag
    Dmel_CG8565
    See related
    AllianceGenome:FB:FBgn0030697
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8565; SPRK2
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of mRNA processing and spliceosomal complex assembly. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK2 (SRSF protein kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8565 in Genome Data Viewer
    Location:
    13F9-13F10; 1-52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15837830..15841160)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15731863..15735193)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Clathrin heavy chain Neighboring gene long non-coding RNA:CR32582 Neighboring gene Arginyl-tRNA synthetase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinctive features of Drosophila alternative splicing factor RS domain: implication for specific phosphorylation, shuttling, and splicing activation. Allemand E, et al. Mol Cell Biol, 2001 Feb. PMID 11158320, Free PMC Article
    2. Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes. Pankotai T, et al. BMC Genomics, 2013 Jan 22. PMID 23336284, Free PMC Article
    3. Genome-wide survey of protein kinases required for cell cycle progression. Bettencourt-Dias M, et al. Nature, 2004 Dec 23. PMID 15616552
    4. Pre-messenger RNA processing factors in the Drosophila genome. Mount SM, et al. J Cell Biol, 2000 Jul 24. PMID 10908584, Free PMC Article
    5. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8565-PA
    NP_573080.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15837830..15841160
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132852.2 → NP_573080.1  uncharacterized protein Dmel_CG8565 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573080.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQ97, Q9VXN5
      Related
      FBpp0073917
      Conserved Domains (1) summary
      cl21453
      Location:192 → 722
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXN5 Q9VXN5

    Gene LinkOut

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