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    CG6984 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6984provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034191
    Locus tag
    Dmel_CG6984
    See related
    AllianceGenome:FB:FBgn0034191
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6984
    Summary
    Predicted to enable enoyl-CoA hydratase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including adult heart; embryonic hindgut; and embryonic/larval midgut primordium. Orthologous to human ECHDC3 (enoyl-CoA hydratase domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6984 in Genome Data Viewer
    Location:
    53F7-53F7; 2-81 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17091984..17093070)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12979489..12980575)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene snoRNA:Orphan CD box 17 Neighboring gene Sphingosine-1-phosphate lyase Neighboring gene Glutathione S transferase S1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reduced Function of the Glutathione S-Transferase S1 Suppresses Behavioral Hyperexcitability in Drosophila Expressing Mutant Voltage-Gated Sodium Channels. Chen HL, et al. G3 (Bethesda), 2020 Apr 9. PMID 32054635, Free PMC Article
    2. Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine. Zhang CH, et al. J Insect Sci, 2019 May 1. PMID 31115476, Free PMC Article
    3. Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. Herr DR, et al. FEBS Lett, 2004 Aug 13. PMID 15304339
    4. Differential evolutionary wiring of the tyrosine kinase Btk. Nawaz HM, et al. PLoS One, 2012. PMID 22574122, Free PMC Article
    5. The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. Zhang Y, et al. EMBO J, 2016 May 17. PMID 27053724, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables enoyl-CoA hydratase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables hydro-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6984-PA
    NP_611187.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17091984..17093070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137343.3 → NP_611187.1  uncharacterized protein Dmel_CG6984 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611187.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1C3
      Related
      FBpp0086132
      Conserved Domains (1) summary
      cl23717
      Location:24 → 283
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K1C3 Q7K1C3

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