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    PET127 Pet127p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854182, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PET127
    Official Full Name
    Pet127p
    Primary source
    SGD:S000005543
    Locus tag
    YOR017W
    See related
    AllianceGenome:SGD:S000005543; FungiDB:YOR017W; VEuPathDB:YOR017W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in mitochondrial RNA 5'-end processing. Located in mitochondrial envelope. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PET127 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (361412..363814)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Erp4p Neighboring gene Rod1p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pet127 governs a 5' -> 3'-exonuclease important in maturation of apocytochrome b mRNA in Saccharomyces cerevisiae. Fekete Z, et al. J Biol Chem, 2008 Feb 15. PMID 18086665
    2. Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA. Corbi D, et al. PLoS Genet, 2021 Oct. PMID 34665800, Free PMC Article
    3. Pet127p, a membrane-associated protein involved in stability and processing of Saccharomyces cerevisiae mitochondrial RNAs. Wiesenberger G, et al. Mol Cell Biol, 1997 May. PMID 9111353, Free PMC Article
    4. Cbp1 is required for translation of the mitochondrial cytochrome b mRNA of Saccharomyces cerevisiae. Islas-Osuna MA, et al. J Biol Chem, 2002 Oct 11. PMID 12149267
    5. Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: an indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs. Wegierski T, et al. Acta Biochim Pol, 1998. PMID 10397341

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results support the hypothesis that Mss116p and Pet127p are involved in modulation of mtRNAP activity.
      Title: Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial RNA 5'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial RNA 5'-end processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial RNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pet127p
    NP_014660.1
    • Protein with a role in 5'-end processing of mitochondrial RNAs; located in the mitochondrial membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      361412..363814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183436.1 → NP_014660.1  TPA: Pet127p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014660.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W283, P32606
      UniProtKB/TrEMBL
      C7GLE7
      Conserved Domains (1) summary
      pfam08634
      Location:242 → 540
      Pet127; Mitochondrial protein Pet127
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32606.2

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