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    Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [ Mus musculus (house mouse) ]

    Gene ID: 67973, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mphosph10provided by MGI
    Official Full Name
    M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)provided by MGI
    Primary source
    MGI:MGI:1915223
    See related
    Ensembl:ENSMUSG00000030521 AllianceGenome:MGI:1915223
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810453H10Rik; 5730405D16Rik
    Summary
    Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in chromosome and nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is expressed in esophagus; lung; pituitary gland; urethra; and vertebral axis musculature. Orthologous to human MPHOSPH10 (M-phase phosphoprotein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E11.5 (RPKM 16.9), liver E14 (RPKM 10.4) and 11 other tissues See more
    Orthologs
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    Genomic context

    See Mphosph10 in Genome Data Viewer
    Location:
    7 34.64 cM; 7 C
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64026289..64041984, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64376541..64392236, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19037 Neighboring gene myotubularin related protein 10 Neighboring gene STARR-seq mESC enhancer starr_19038 Neighboring gene STARR-seq mESC enhancer starr_19039 Neighboring gene SET translocation pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:71537088-71537271 Neighboring gene STARR-positive B cell enhancer ABC_E4931 Neighboring gene FANCD2/FANCI-associated nuclease 1 Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene STARR-seq mESC enhancer starr_19041 Neighboring gene STARR-seq mESC enhancer starr_19042

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Mpp10 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Mpp10 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Mpp10 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of sno(s)RNA-containing ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    U3 small nucleolar ribonucleoprotein protein MPP10
    Names
    m phase phosphoprotein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026483.2NP_080759.2  U3 small nucleolar ribonucleoprotein protein MPP10

      See identical proteins and their annotated locations for NP_080759.2

      Status: VALIDATED

      Source sequence(s)
      AK008785, AK017490, AV222458, CK390971
      Consensus CDS
      CCDS21333.1
      UniProtKB/Swiss-Prot
      E9QM78, Q810V0
      UniProtKB/TrEMBL
      A0PJ89
      Related
      ENSMUSP00000032735.6, ENSMUST00000032735.8
      Conserved Domains (1) summary
      pfam04006
      Location:22632
      Mpp10; Mpp10 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      64026289..64041984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)