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    Gm14295 predicted gene 14295 [ Mus musculus (house mouse) ]

    Gene ID: 100039123, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Gm14295provided by MGI
    Official Full Name
    predicted gene 14295provided by MGI
    Primary source
    MGI:MGI:3709624
    See related
    Ensembl:ENSMUSG00000078877 AllianceGenome:MGI:3709624
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Broad expression in cortex adult (RPKM 6.2), frontal lobe adult (RPKM 6.2) and 22 other tissues See more
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    Genomic context

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    See Gm14295 in Genome Data Viewer
    Location:
    2 H4; 2 99.06 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (176489972..176512508)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (176798179..176814092)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14305 Neighboring gene zinc finger protein 937 pseudogene Neighboring gene STARR-seq mESC enhancer starr_06660 Neighboring gene predicted gene 14408 Neighboring gene predicted gene 14405

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100039123
    Names
    KRAB box and zinc finger, C2H2 type domain containing
    novel KRAB box and zinc finger, C2H2 type domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205057.2 → NP_001191986.1  uncharacterized protein LOC100039123

      See identical proteins and their annotated locations for NP_001191986.1

      Status: VALIDATED

      Source sequence(s)
      BC083167, BC106197, CO428255
      Consensus CDS
      CCDS57201.1
      UniProtKB/TrEMBL
      A2BG90, J3QMJ8, Q8C1K5, Q8CFP2
      Related
      ENSMUSP00000113133.3, ENSMUST00000118012.9
      Conserved Domains (2) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      pfam01352
      Location:4 → 43
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      176489972..176512508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245890.2 → XP_030101750.1  uncharacterized protein LOC100039123 isoform X2

      UniProtKB/TrEMBL
      A2BG91
      Related
      ENSMUSP00000119262.2, ENSMUST00000132883.8
      Conserved Domains (4) summary
      COG5048
      Location:395 → 795
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box
      pfam13465
      Location:118 → 142
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030245886.2 → XP_030101746.1  uncharacterized protein LOC100039123 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:414 → 814
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:432 → 452
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:22 → 63
      KRAB; KRAB box
      pfam13465
      Location:137 → 161
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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