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    BC051665 cDNA sequence BC051665 [ Mus musculus (house mouse) ]

    Gene ID: 218275, updated on 9-Dec-2024

    Summary

    Official Symbol
    BC051665provided by MGI
    Official Full Name
    cDNA sequence BC051665provided by MGI
    Primary source
    MGI:MGI:2682300
    See related
    Ensembl:ENSMUSG00000042243 AllianceGenome:MGI:2682300
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable cysteine-type endopeptidase activator activity involved in apoptotic process and cysteine-type endopeptidase activity. Predicted to be involved in immune response; positive regulation of apoptotic signaling pathway; and proteolysis involved in protein catabolic process. Predicted to be active in extracellular space and lysosome. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See BC051665 in Genome Data Viewer
    Location:
    13 B2; 13 32.53 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (60929701..60934178, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (60781887..60786364, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A530001N23 gene Neighboring gene STARR-seq mESC enhancer starr_34736 Neighboring gene STARR-seq mESC enhancer starr_34737 Neighboring gene STARR-seq mESC enhancer starr_34738 Neighboring gene STARR-seq mESC enhancer starr_34740 Neighboring gene death associated protein kinase 1 Neighboring gene predicted gene, 35540 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:60839367-60839520 Neighboring gene STARR-seq mESC enhancer starr_34741 Neighboring gene cathepsin L-like 3 Neighboring gene STARR-seq mESC enhancer starr_34742 Neighboring gene RIKEN cDNA 4930486L24 gene Neighboring gene STARR-seq mESC enhancer starr_34743

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Clone Names

    • MGC60730

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC218275

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199148.2NP_954599.2  uncharacterized protein LOC218275 precursor

      Status: VALIDATED

      Source sequence(s)
      AK145559, BC051665, CJ076391
      Consensus CDS
      CCDS26582.1
      UniProtKB/TrEMBL
      E9Q623, Q80X23
      Related
      ENSMUSP00000026078.9, ENSMUST00000026078.10
      Conserved Domains (3) summary
      PTZ00203
      Location:7326
      PTZ00203; cathepsin L protease; Provisional
      smart00848
      Location:2987
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:114329
      Peptidase_C1; Papain family cysteine protease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      60929701..60934178 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)