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    NANS N-acetylneuraminate synthase [ Sus scrofa (pig) ]

    Gene ID: 100155883, updated on 11-Jan-2025

    Summary

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    Official Symbol
    NANSprovided by VGNC
    Official Full Name
    N-acetylneuraminate synthaseprovided by VGNC
    Primary source
    VGNC:VGNC:112521
    See related
    Ensembl:ENSSSCG00000005373
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in ovary (RPKM 24.4), spleen (RPKM 18.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See NANS in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (239881984..239912727)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (268051524..268082265)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene acidic nuclear phosphoprotein 32 family member B Neighboring gene ferritin light chain-like Neighboring gene tripartite motif containing 14 Neighboring gene coronin 2A Neighboring gene TBC1 domain family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables N-acylneuraminate-9-phosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sialic acid synthase
    Names
    N-acetylneuraminic acid synthase
    NP_001172068.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001185139.1 → NP_001172068.1  sialic acid synthase

      See identical proteins and their annotated locations for NP_001172068.1

      Status: PROVISIONAL

      Source sequence(s)
      AB529862
      UniProtKB/TrEMBL
      A0A4X1U234, A0A8D1URH6, D0G780
      Related
      ENSSSCP00000050044.2, ENSSSCT00000055524.3
      Conserved Domains (3) summary
      cd11615
      Location:292 → 348
      SAF_NeuB_like; C-terminal SAF domain of sialic acid synthetase
      TIGR03569
      Location:19 → 345
      NeuB_NnaB; N-acetylneuraminate synthase
      pfam03102
      Location:40 → 278
      NeuB; NeuB family

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      239881984..239912727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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