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    ARHGAP19-SLIT1 ARHGAP19-SLIT1 readthrough (NMD candidate) [ Homo sapiens (human) ]

    Gene ID: 100533184, updated on 10-Dec-2024

    Summary

    Official Symbol
    ARHGAP19-SLIT1provided by HGNC
    Official Full Name
    ARHGAP19-SLIT1 readthrough (NMD candidate)provided by HGNC
    Primary source
    HGNC:HGNC:48348
    See related
    Ensembl:ENSG00000269891 AllianceGenome:HGNC:48348
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARHGAP19
    Summary
    This locus represents naturally occurring read-through transcription between the neighboring Rho GTPase activating protein 19 (ARHGAP19) and slit homolog 1 (SLIT1) genes on chromosome 10. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]
    Expression
    Broad expression in testis (RPKM 11.0), lymph node (RPKM 5.6) and 23 other tissues See more
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    Genomic context

    See ARHGAP19-SLIT1 in Genome Data Viewer
    Location:
    10q24.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (97153042..97292673, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (98033905..98172875, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (98912799..99052430, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ligand dependent nuclear receptor corepressor Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 35 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:98744001-98744502 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:98744503-98745002 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98761702-98762390 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98780664-98781497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98790940-98791510 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98791511-98792081 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:98794025-98794781 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98797839-98798339 Neighboring gene slit guidance ligand 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2666 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:98829552-98830751 Neighboring gene Sharpr-MPRA regulatory region 3512 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:98839846-98840622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98850461-98851078 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98860158-98861022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98861023-98861885 Neighboring gene SLIT1 antisense RNA 1 Neighboring gene MPRA-validated peak1061 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98890534-98891034 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98900602-98901342 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3844 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3845 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:98922776-98923310 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:98923311-98923844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98923845-98924378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98945560-98946060 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:98946061-98946561 Neighboring gene uncharacterized LOC112268065 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2667 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3846 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2668 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:98962904-98963503 Neighboring gene uncharacterized LOC105378447 Neighboring gene Rho GTPase activating protein 19 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99027352-99027856 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99049689-99050447 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99051206-99051964 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99051965-99052721 Neighboring gene Sharpr-MPRA regulatory region 7927 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2671 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3847 Neighboring gene ribosomal protein L12 pseudogene 27 Neighboring gene FRAT regulator of WNT signaling pathway 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    General gene information

    Markers

    Other Names

    • Rho GTPase-activating protein 19
    • Rho-type GTPase-activating protein 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_037909.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA431797, AL359385, AY336750
      Related
      ENST00000479633.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      97153042..97292673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      98033905..98172875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)