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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_041780.1 RefSeqGene
- Range
-
5858..46291
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1317
mRNA and Protein(s)
-
NM_001199138.2 → NP_001186067.1 NLR family CARD domain-containing protein 4 isoform a
See identical proteins and their annotated locations for NP_001186067.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has an alternate 5' UTR exon and encodes the same protein, as compared to variant 1.
- Source sequence(s)
-
AK095467, AL121653, BC031555
- Consensus CDS
-
CCDS33174.1
- UniProtKB/Swiss-Prot
- A8K9F8, B2RBQ3, B3KTF0, D6W580, Q96J81, Q96J82, Q96J83, Q9NPP4
- Related
- ENSP00000385428.1, ENST00000402280.6
- Conserved Domains (5) summary
-
- cd00116
Location:738 → 978
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- sd00033
Location:738 → 764
- LRR_RI; leucine-rich repeat [structural motif]
- sd00034
Location:691 → 713
- LRR_AMN1; leucine-rich repeat [structural motif]
- pfam00619
Location:1 → 87
- CARD; Caspase recruitment domain
- pfam05729
Location:163 → 316
- NACHT; NACHT domain
-
NM_001199139.1 → NP_001186068.1 NLR family CARD domain-containing protein 4 isoform a
See identical proteins and their annotated locations for NP_001186068.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has an alternate splice site in the 5' UTR and encodes the same protein, as compared to variant 1.
- Source sequence(s)
-
AW337918, AY035391
- Consensus CDS
-
CCDS33174.1
- UniProtKB/Swiss-Prot
- A8K9F8, B2RBQ3, B3KTF0, D6W580, Q96J81, Q96J82, Q96J83, Q9NPP4
- Conserved Domains (5) summary
-
- cd00116
Location:738 → 978
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- sd00033
Location:738 → 764
- LRR_RI; leucine-rich repeat [structural motif]
- sd00034
Location:691 → 713
- LRR_AMN1; leucine-rich repeat [structural motif]
- pfam00619
Location:1 → 87
- CARD; Caspase recruitment domain
- pfam05729
Location:163 → 316
- NACHT; NACHT domain
-
NM_001302504.1 → NP_001289433.1 NLR family CARD domain-containing protein 4 isoform b
See identical proteins and their annotated locations for NP_001289433.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform b, which is shorter than isoform a.
- Source sequence(s)
-
AL121653, AW337918, AY027788
- Consensus CDS
-
CCDS77400.1
- UniProtKB/Swiss-Prot
-
Q9NPP4
- Related
- ENSP00000339666.6, ENST00000342905.10
- Conserved Domains (4) summary
-
- COG4886
Location:79 → 329
- LRR; Leucine-rich repeat (LRR) protein [Transcription]
- cd00116
Location:71 → 313
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- sd00033
Location:100 → 124
- LRR_RI; leucine-rich repeat [structural motif]
- pfam00619
Location:1 → 87
- CARD; Caspase recruitment domain
-
NM_021209.4 → NP_067032.3 NLR family CARD domain-containing protein 4 isoform a
See identical proteins and their annotated locations for NP_067032.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
- Source sequence(s)
-
AW337918, BC031555, DN998613
- Consensus CDS
-
CCDS33174.1
- UniProtKB/Swiss-Prot
- A8K9F8, B2RBQ3, B3KTF0, D6W580, Q96J81, Q96J82, Q96J83, Q9NPP4
- Related
- ENSP00000354159.5, ENST00000360906.9
- Conserved Domains (5) summary
-
- cd00116
Location:738 → 978
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- sd00033
Location:738 → 764
- LRR_RI; leucine-rich repeat [structural motif]
- sd00034
Location:691 → 713
- LRR_AMN1; leucine-rich repeat [structural motif]
- pfam00619
Location:1 → 87
- CARD; Caspase recruitment domain
- pfam05729
Location:163 → 316
- NACHT; NACHT domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
32224449..32265743 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047445356.1 → XP_047301312.1 NLR family CARD domain-containing protein 4 isoform X1
- UniProtKB/TrEMBL
-
A0A499FIV7
- Related
- ENSP00000385090.3, ENST00000404025.3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
32272955..32314278 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054343247.1 → XP_054199222.1 NLR family CARD domain-containing protein 4 isoform X1
- UniProtKB/TrEMBL
-
A0A499FIV7