U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FMP40 Fmp40p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855879, updated on 9-Dec-2024

    Summary

    Official Symbol
    FMP40
    Official Full Name
    Fmp40p
    Primary source
    SGD:S000006143
    Locus tag
    YPL222W
    See related
    AllianceGenome:SGD:S000006143; FungiDB:YPL222W; VEuPathDB:YPL222W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables AMPylase activity. Involved in cell redox homeostasis and protein adenylylation. Is active in mitochondrion. Orthologous to human SELENOO (selenoprotein O). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FMP40 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (130162..132228)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mmt2p Neighboring gene Gre1p Neighboring gene flavin adenine dinucleotide transporter Neighboring gene ribosomal 60S subunit protein L1A

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables AMPylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables AMPylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables AMPylase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein adenylylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Fmp40p
    NP_015102.1
    • Mitochondrial AMPylator in the pseudokinase selenoprotein-O family; role in the oxidative stress response, transferring AMP from ATP to protein substrates (AMPylation) involved in redox homeostasis; regulates S-glutathionylation levels; proposed involvement in the environmental stress response

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      130162..132228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184036.1NP_015102.1  TPA: Fmp40p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015102.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3E8, Q08968
      UniProtKB/TrEMBL
      A6ZW33, B3LKK8, B5VSV9, C7GN49, C8ZIF7, N1NWM1
      Conserved Domains (1) summary
      COG0397
      Location:29688
      YdiU; Uncharacterized conserved protein YdiU, UPF0061 family [Function unknown]