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    RPS8A ribosomal 40S subunit protein S8A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852206, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS8A
    Official Full Name
    ribosomal 40S subunit protein S8A
    Primary source
    SGD:S000000168
    Locus tag
    YBL072C
    See related
    AllianceGenome:SGD:S000000168; FungiDB:YBL072C; VEuPathDB:YBL072C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS8A in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (88523..89125, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene U5 snRNP complex subunit AAR2 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Kti11p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation. Papai G, et al. Nature, 2010 Jun 17. PMID 20559389, Free PMC Article
    2. Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae. Gómez-Herreros F, et al. J Biol Chem, 2013 Nov 1. PMID 24043628, Free PMC Article
    3. Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth. Ghalei H, et al. J Cell Biol, 2015 Mar 16. PMID 25778921, Free PMC Article
    4. The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. Sardana R, et al. PLoS Biol, 2015 Feb. PMID 25710520, Free PMC Article
    5. Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome. Pech M, et al. J Biol Chem, 2010 Jun 18. PMID 20410297, Free PMC Article

    See all (123) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S8A
    NP_009481.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S8, no bacterial homolog; RPS8A has a paralog, RPS8B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      88523..89125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178312.1 → NP_009481.1  TPA: ribosomal 40S subunit protein S8A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009481.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2TBM0, A2TBP0, D3DM09, P05754, P0CX39, P0CX40, P22801
      UniProtKB/TrEMBL
      A6ZKM8, A6ZR58, B3LNK6, B3LRM0, B5VHM8, C8Z3S1, G2W8T8, G2WD21, N1P719
      Conserved Domains (1) summary
      PTZ00148
      Location:1 → 200
      PTZ00148; 40S ribosomal protein S8; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX39.1
    P0CX40.1

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