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    mst2 histone acetyltransferase Mst2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542170, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mst2
    Official Full Name
    histone acetyltransferase Mst2
    Primary source
    PomBase:SPAC17G8.13c
    Locus tag
    SPOM_SPAC17G8.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mst2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (2363499..2366934, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene exocyst complex subunit Sec3 Neighboring gene protein kinase C (PKC)-like Pck1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation. Nugent RL, et al. BMC Genomics, 2010 Jan 22. PMID 20096118, Free PMC Article
    2. Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Kiely CM, et al. Mol Cell Biol, 2011 Oct. PMID 21844224, Free PMC Article
    3. Rapid epigenetic adaptation to uncontrolled heterochromatin spreading. Wang J, et al. Elife, 2015 Mar 16. PMID 25774602, Free PMC Article
    4. Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26. Hirota K, et al. Mol Biol Cell, 2008 Mar. PMID 18199689, Free PMC Article
    5. Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing. Gómez EB, et al. Mol Cell Biol, 2005 Oct. PMID 16199868, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone H3K14 acetyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin boundary formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in heterochromatin formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Mst2 histone acetyltransferase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of NuA3a histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    histone acetyltransferase Mst2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2363499..2366934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019167.3 → NP_593736.1  histone acetyltransferase Mst2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593736.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10325
      Conserved Domains (2) summary
      COG5027
      Location:1 → 370
      SAS2; Histone acetyltransferase (MYST family) [Chromatin structure and dynamics]
      cl17182
      Location:102 → 372
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    Nucleotide Protein
    Heading Accession and Version

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