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    brx1 ribosome biogenesis protein brx1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540268, updated on 18-Sep-2024

    Summary

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    Official Symbol
    brx1
    Official Full Name
    ribosome biogenesis protein brx1
    Primary source
    PomBase:SPBC800.06
    Locus tag
    SPOM_SPBC800.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See brx1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (262572..263669)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein eL43 Neighboring gene ncRNA Neighboring gene tubulin alpha 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation elongation factor EF-Ts Tsf1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts. Wan K, et al. Yeast, 2015 Sep. PMID 26122634
    2. The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection. Lemay JF, et al. Genes Dev, 2016 Jul 1. PMID 27401558, Free PMC Article
    3. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
    4. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Ugolini I, et al. Mol Cell, 2022 Dec 1. PMID 36423630, Free PMC Article
    5. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in assembly of large subunit precursor of preribosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of preribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribosome biogenesis protein brx1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      262572..263669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021014.3 → NP_595107.1  ribosome biogenesis protein brx1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595107.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HGL6
      Conserved Domains (1) summary
      COG5154
      Location:1 → 295
      BRX1; RNA-binding protein required for 60S ribosomal subunit biogenesis [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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